It’s something I see brought up a lot. People always point to the plot of Bioshock as a individualist, capitalist society directly leading to mental illness, drug addiction, and poverty.
Personally, I don’t even like Ayn Rand; my opinions on objectivism are lukewarm at best, and I think most of her “classics” are only classics because they’re old. But Bioshock is just one giant strawman of everything she’s ever said.